For times when you find yourself engaged in a research project or otherwise tab-heavy browsing session, there is Tab Resize for Chrome. This extension lets you split tabs into multiple windows, arranged in a number of preset layouts. It's particularly useful on larger displays.
Tab Resize installs a button to the right of the URL bar in Chrome. Click on it and you'll see a number of layouts from which to choose. If you don't like any of the layouts, you can create a custom layout; simply name the number of rows and columns and it's at your disposal. Going the other way, you can remove a template from the Tab Resize window by hovering over it and clicking the small X in the upper-right corner of its box.
Tab Resize sees only your active tab and those to the right of it. Thus, you'll get an empty layout if you choose a Tab Resize template when viewing the right-most tab in Chrome. And you'll get only a partially filled layout if you select a layout with more windows than you have tabs to the right of your active tab.
It's easy to undo Tab Resize and return to a single Chrome window with your tabs arranged as before. Just click on the Tab Resize button and click the Undo button.