You should be able to go to the Programs & Features applet of the Control Panel and do a repair. When you find the Microsoft Office entry, right-click it and click Change. Then click Repair. That has worked for me in the past. I'd also boot to Safe Mode and do a check for viruses. You could also go to an elevated command prompt and issue the command sfc /scannow to check for corrupt system files.
I have a client who is a Windows 7 Pro x64 user on a domain using Office 2010. When he opens Word and starts a new document, from the File menu, clicking Save, Save As or Open will do nothing but return him to the Home tab viewing the document. There is no error, no indication that Word is trying to do something, it just goes back to the document view.
I checked his Save options to see what the default save location is and it is set to save to the network share, but pressing the Browse button to the right has no effect.
It appears that any action that Word tries to do that requires opening a browse window fails. If I select Save and Send from the File menu, I can successfully email the document, but it is titled Document1, but doesn't save it in the default location for the machine. Tried starting Word in Safe mode and get the same result. When I log in to the computer using admin creds, Word works just fine. I logged in as another user who had never logged in to that computer before and it worked fine. Tried renaming his account profile and forcing Windows to create a new user profile for him, but it wouldn't create the new profile, if pushed it into a temporary user account. Thinking it might have been something quirky or corrupted with his domain account, I logged in to another computer in the domain using his creds and Word works fine, his profile gets created normally.
I deleted Normal.dotm; I deleted the Word registry entries in HK_CU_Software_Microsoft_Office_14.0; I have attempted repair installations twice. My next step is to uninstall and reinstall Word, then a complete system wipe. I'm hesitant, though, because Word works on other user profiles.
What am I missing? Any other suggestions?