Have a look at TrueCrypt. A wee bit of a learning curve, but worth it.
I wish to secure/lock a few folders on my laptop which have personal information. I see there is one software called File Lock and another Krypton? I wish to be able to unlock these folders, use them and lock them again after use. I just had my laptop stolen and although it was password protected (I know that isn't everything) I worry about information in some files. Now that I have a new laptop I wish to secure future folders so that if anything every happens again, I do not have this concern. I have been worried sick. thank you