Although I've used older versions of both tools previously, just as a test, our advice regarding such "optimizers" and registry cleaners is they usually do more harm than good. In my previous tests, (not specifically of the new versions you've listed), after running a cleanup scan of a brand new installation of Windows, which surprisingly found hundreds of "faults" in the system, I let the tools remove the "problems" found.. After a restart of the system, I ran the same scans again.. Hmmm, the tools found LOTS of "problems" again.. Makes one suspicious of the validity of their scans.
In addition, since I have never been able to find a good third-party testing site of such programs, it's clear to me they are basically useless.. Most importantly, discussions about this topice generally indicate such programs provide little to no performance increase anyway.
And in many cases, they're worse than useless, they frequently remove important files and registry entries which cause computers to run poorer than before.. Sometimes, the computers cease to function at all.
As a general rule, unless you've got enough knowledge and experience to approve each of the files and registry items the programs identify as "bad", why let such a tool run on your machine?
Hope this helps.