I'd do the usual scans with Adaware, Spybot, Stinger and Housecall. And read the Shutdown Article at http://www.aumha.org/articles.htm
After about one hour after I turn my computer on everything starts slowing down, where I will have dispaly lags while typing, and the mouse pointer will seem hung up when moving around on the screen.
I have tried getting rid of uneeded downloaded, but nothing seems to bring it back up to speed.
Also, my computer will no longer "Shut down" or "restart". (???)