First off, take a look at the thread from Grif: http://forums.cnet.com/7726-6132_102-5098912.html?tag=posts;msg5165373
Do exactly as indicated in the thread. It may require getting some things while using an uninfected computer. If that does not do the trick, come back with results from the aforementioned activity, or preform a Recovery from the manufacturer's Recovery method. Most all provide a way to return the PC to like new condition.
If the make and model is provided, we can help if that is the route to take, then that will take care of the problem.
So my friends computer just today crashed from a ransomware virus, talking about illegal music and asking for 120 dollars. We cant get the computer to start up in any safe mode, in normal mode, or with a windows install disk. She can never get to her desktop or even a log in screen. Eventually her computer will just stop and freeze at some point before that. Help!