What won't run (assuming it won't launch or crashes) will probably have to be re-installed. Windows 2000 and XP actually had a lot of commonality, but some thing just don't transfer without a re-install. I'm not sure a repair will work for office, but maybe. However you installed Autocad the first time, repeat it. If disk lost contact them give them the current license and ask for a replacement CD. Probaly cost you the media. In some cases it might be a driver issue and you can research the differences or patches required to support W2K software. Past that not much you can do.