Generally, application programs don't 'work with' antivirus programs. They are independent. So most likely, it will work.

But, of course, you don't want to install something in youjr production environment that you aren't sure of. So the thing to do is to install that PC Tools program on your test machine (backup machine, whatever you call it) and try.

It might be cheaper to use a paid anti-virus program, unless both the test machine and your hours spent on the test are free.