I have a one year old Satellite L755 (running Windows 7) and have that problem with the right side USB ports. When I plug the mouse into the left side port, it works. I have no idea why, but it's easy enough to do, so I've never bothered asking why.
I received a Toshiba Satellite Laptop (S855-S5377) for Christmas and it is running Windows 8. I started using it and it worked fine, but I started using Internet Explorer and the mouse froze, but I could still use my keyboard to get back to the start-page and move around with the up/down/left/right keys. My mouse was no where to be found on the start-page. I used the ctrl-alt-delete to log out, and then when the log-in screen came up my mouse reappeared and seemed to be working again. I logged back in and my mouse worked for a few seconds, then disappeared. I did the same things over and over again a few times, and either the mouse was nowhere to be found from the get-go, or it worked for a bit then disappeared once I started doing things. I shut down, and restarted multiple times. Any fix for this problem? If it is a Windows 8 problem I am very disappointing at the moment with the software. Thank you, and happy holidays.