your scanner should be able to quarantine this. Have a look at their "Solutions" tab here;
http://threatinfo.trendmicro.com/vinfo/virusencyclo/default5.asp?VName=JS_DLDR.SMA&VSect=Sn

I would scan again. They mention disabling System Restore for ME and XP users and I would be inclined to do the same for your Vista OS. Be sure to re-enable SR after the scan and create your own restore point immediately.

If that fails, then start getting second opinions with Malwarebytes' Anti-malware and SUPERAntiSpyware.

Hope that helps.

Mark