1. What is your homepage?
2. Does it work if you select a different homepage?
3. Tried resetting the home page by navigating to your homepage manually, then open Internet Options, then in the "General" tab, click on the "Use Current" button, then "Apply", then OK.
4. If you haven't already and because "About:blank" could possibly be related to a malware infection, please download, install, update, then run a full system scan with BOTH of the free malware scanners below:
SUPERAntispyware Removal Tool
Hope this helps and let us know more.
When I click on my IE icon on my desktop, I get a blank screen with (about:blank) in the address bar. I have tried to go to Tools>Internet Options>General Tab and (about:blank) is in the homepage tab box also. I have tried to change it both by putting the homepage URL directly in, and have clicked on use current while on my regular homepage.
My OS is XP, and my browsere is IE8.
Any help will be greatly appreciated.