Sorry, but none of the mods here use such programs. So we can't speak out of experience. And any member that answers most likely only has experience with one of the two.
So I'm afraid you'll have to make your own choice based on not much advice.
In the last two days I got license keys for them both and right now I am using Advanced Systemcare from a previous license, but which one is better?
From the looks of it Advanced Systemcare has more than you could get for free if you were to use the free version and it looks like Glary Utilities doesn't offer much more useful features in the pro version. Only like updating and stuff that really doesn't matter like scheduling.
Another thing that I would take into consideration is the automatic defrag. Smart Defrag has this but does Disk Speedup?