You can either learn more about ownership, permissions and safe mode or just boot some other OS from CD to reach in and delete them. I find folk rarely want to use the NTFS permissions and such and some don't want to boot another live CD or OS.
Which method will you use?
Have a question - I get a message stating a dll operation has failed - wow.dll and the location of the files is described as C:\User....\Appdata\Local\Temp\spkrmmj\sesnrxw\wow.dll. When I attempt to access the file folders beyond Temp, access is denied. Bad stuff going on, I would like to know how I can get to and erase those files and folders. Enabling hidden folders doesn't work, so I need some additional advice/assistance. Thanks