I suggest checking your comodo internet security/windows defender software if it can block port 80 (and 443 while you're at it) at a particular network card. You really cannot bind any OSI layer 4-7 protocols to an ethernet card, only OSI layer 3, but you can block any OSI layer 4-8 protocol if your firewall has the capability.

OSI info: http://en.wikipedia.org/wiki/Osi_layer