What spyware/adware/malware have you searched for? Try AdAware, Spybot Search & Destroy, and Spyware Blaster, all free, do a Google for them.
I use these to "finish up"; CCleaner, RegscrubXP, and EasyCleaner. Google.
How do I know what I can safely remove from my computer?
I know my register needs a purge, my computer system is so constipated I can no longer send or receive emails! But being as I am computer-jargon illiterate, I am nervous that it will remove something of importance causing in the end more problems than it solved.
Any help would be greatly appreciated.