offspring

Stem cells used to create sperm in infertile mice

Welcome to mating 2.0: the sexual act itself might not change, but when the parts don't work, we'll simply build new ones.

So say scientists in Japan who, using stem-cell techniques, are the first to engineer sperm in infertile male mice that successfully fertilized eggs and produced offspring.

The team, led by Mitinori Saitou at Kyoto University, report in the journal Cell that it used stem cells to create primordial germ cells, the precursor to sperm cells, and injected those germ cells into the testicles of infertile mice. The cells eventually produced normal-looking sperm, which went on … Read more