genetic

Sometimes a concept is simple but the tech behind it is not. This is the case with a new approach to identifying new viruses, which could ultimately lead to screening patients for viruses that haven't even been identified. (Think of the one currently rearing its deadly head in the Middle East.)

Researchers at Saint Louis University are using the next-gen sequencing approach transcriptome subtraction, and it really does employ basic arithmetic -- with very fancy tools. They take a human blood sample. Then they subtract the entire human genetic sequence from the genetic material in the sample. Then they … Read more

A researcher who used to work in digital television has just led a team of Columbia University engineers to win the Sage Bionetworks / DREAM Breast Cancer Prognosis Challenge.

Dimitris Anastassiou, who is now a systems biologist (meaning he investigates interactions within biological systems), reports in the April 17 issue of Science Translational Medicine that his team's winning computation model is extremely predictive of breast cancer survival.

Before the challenge, Anastassiou and his team identified what they call "attractor metagenes," which are genetic signatures expressed in almost the exact same way across many types of cancer. Their new … Read more

Internet addiction is real, researchers out of the University of Bonn say, and its source can be explained at the molecular level.

Researchers from the school's departments of psychology and neuroscience report in the September 2012 issue of the Journal of Addiction Medicine that a simple variation on the CHRNA4 gene results in a significantly higher prevalence of Internet addiction -- and particularly in women.

"Internet addiction is not a figment of our imagination," lead author Christian Montag says in a news release. "The current data already shows that there are clear indications for genetic causes of Internet addiction... If such connections are better understood, this will also result in important indications for better therapies."… Read more

What if tobacco could grow fuel in its leaves?

As far-fetched as that sounds, a group of scientists at Lawrence Berkeley National Lab is testing the limits of genetic engineering to make the widely grown tobacco plant a carrier for hydrocarbons.

Scientists will be at the ARPA-E Energy Innovation Summit this week to discuss the project, which received a $4.8 million grant over three years. The grant fits ARPA-E's mission of funding research that is high-risk but with a potential for a breakthrough.

Biofuels or biochemicals are typically made by growing plants and then converting that biomass into … Read more

It's been a good year for video gamers--and not just the epic legions of Call of Duty fans enjoying Modern Warfare 3.

A few months after Foldit players helped decode the structure of a protein key to the way HIV multiplies, another group of gamers taking on DNA sequencing in the game Phylo have contributed more than 350,000 solutions, the game's designers at McGill University report.

When University of Washington researchers unveiled Foldit in 2008, it wasn't clear whether the protein-folding game would be a one hit wonder. But one-year-old Phylo, already averaging 1,000 eureka … Read more

What does it take to make it to 100 years old? The Archon Genomics X Prize hopes to find out.

As I've researched "extreme" aging in recent years--that is, the genes and lifestyles of centenarians (100 and older) and supercentenarians (110 and older)--a common refrain I hear from my younger peers is, "I don't want to get that old. It sounds miserable."

Whether or not that's true is something most of us will never find out. The reality is that those who make it past 100 are an exceedingly rare breed of … Read more

Researchers have invented a silicone lab on a chip they say could make genetic analysis far more sensitive--not to mention rapid and cost-effective--by routing fluid through microscopic tubes and valves, and allowing individual cells to fall into place much like balls in a pinball machine.

Standard genetic testing involves vast numbers of cells that, when analyzed, provide a sort of composite picture that cannot reveal the behaviors of individual cells.

"It's like trying to understand what makes a strawberry different from a raspberry by studying a blended-fruit smoothie," said Carl Hansen, an assistant professor who led the … Read more

Drug companies have long used plants to produce pharmaceuticals--and tobacco plants, perhaps ironically, have been explored for their potential role in fighting such things as cancer, cavities, scorpion venom, and more.

The latest big news, announced at a press conference in London this morning, is that U.K. regulators have, for the first time, approved a human clinical trial of a monoclonal antibody produced using genetically modified tobacco plants.

Monoclonal antibodies are made from identical immune cells that have been cloned from a unique parent cell to fulfill a specific role. The roots of this idea, which date back more … Read more

MEDFORD, Mass.--In this densely populated city outside Boston without a farm in sight, agriculture researchers are engineering corn and other crops to become better biofuels.

U.S. Secretary of Agriculture Tom Vilsack last week visited Agrivida, a small company working on a method it hopes will help deliver on the biofuels industry's promise of economically making fuel and chemicals from non-food crops. Vilsack toured the lab of Agrivida to draw attention to federal investments in renewable energy research and development.

Cheaper biofuels will help lower fuel costs and provide economic development in rural areas of the U.S., … Read more