diabetes

As recently as the 1950s, one in three people diagnosed with Type 1 diabetes died within 25 years of diagnosis. People in the '50s had to monitor their glucose levels via urine testing and inject themselves with animal-derived insulin.

How far we've come. Today, researchers are working to develop an artificial pancreas for people with Type 1 diabetes that works with a smartphone or tablet to both monitors blood glucose levels and disperses insulin 24/7.

The goal, they say, is to reduce complications and improve the life expectancy of the millions of people with the metabolic disease -- because even though only 7 percent of them now die within 25 years of diagnosis, this rate is still far above general population mortality.… Read more

Nowadays breathalyzers are being used to detect far more than just how much alcohol one has imbibed. Researchers in Sweden are working on one that can spot marijuana and cocaine. Scientists in Germany are exploring one that can sniff out heart failure. And researchers in the U.S. are hard at work on one that can detect diseases such as diabetes.

And now, a group of chemists at the University of Pittsburgh is unveiling new sensor technology that could lead to a breathalyzer for not just the detection of diabetes, but the ongoing monitoring of it as well.… Read more

For diabetics who have to constantly manage their blood-sugar levels, insulin works. The problem is, many people with Type 1 diabetes have to prick their fingers multiple times a day to monitor their levels, and inject themselves with insulin when those levels are too high. And they don't always administer the right amount at the right time.

Researchers at the Massachusetts Institute of Technology and Boston Children's Hospital hope to automate insulin delivery with a novel nanotech approach that involves injecting a gel that detects blood-sugar levels and secretes insulin when needed -- with a single injection doing do the trick for as many as 10 days.… Read more

What if you could "street view" the human body, navigating its interactive components all the way down to a metabolic level? An international group of scientists is working on that right now with a map of the human metabolism, which they call Recon 2.

Metabolism plays a key role in many diseases, and while scientists have already managed to reconstruct several models of it, each "represents only a subset of our knowledge" with "only partially overlapping content," the team writes in the journal Nature Biology.

"It's like having the coordinates of all the cars in town, but no street map," Bernhard Palsson, a professor of bioengineering at the University of California San Diego Jacobs School of Engineering and one of the authors of the paper, said in a statement. "Without this tool, we don't know why people are moving the way they are."… Read more

Ever thought a smartphone could detect what was in your urine? Well, now it can. A new iPhone app, developed by MIT entrepreneur Myshkin Ingawale and unveiled at the TED conference this week, lets people take urine samples with their mobile device.

Obviously, pee and electronics don't mix, so this app instead uses the smartphone's camera to determine what's in urine. Dubbed Uchek, the app involves the user peeing into a cup, putting a color-coded urinalysis strip into the cup, taking of photo of the results, and then letting the app work its magic.… Read more

Oxford University Ph.D. student Jessica Richman, who today finished raising some $350,000 from more than 2,500 people wanting to take part in the uBiome project, isn't shying away from reality: "Yes, we are going to be sampling people's poo," she told the Guardian this week.

And for the squeamish, she offered an asterisk: "You'll only have to wipe it on the toilet paper."

The uBiome project is a "citizen science" effort to sequence the genomes of the trillions of bacteria that colonize our bodies and likely play pivotal … Read more

When it comes to certain diseases -- think heart disease, diabetes, and various cancers -- some basic lifestyle changes are the best preventive medicine.

And while most of us know to eat a balanced diet, exercise, and abstain from smoking, it can be far more motivating to make healthy changes if we also know we're prone to certain diseases.

Enter Zuum, a free new iPad app that estimates your risk of common diseases and personalizes tips to prevent them and improve your overall health.… Read more

Within a couple years, a single exhale may tell us more about our personal health than merely the current state of our oral hygiene -- and without relying on dogs to sniff out our problems.

The answer lies in a device called the Single Breath Disease Diagnostics Breathalyzer. Back in 2010, Stony Brook University researcher Perena Gouma began testing an earlier iteration in preclinical trials; for use with diabetes patients; now she has developed a sensor that might enable the detection of a range of diseases in a single exhale.

The sensor, which lives in a device about half the … Read more

Glucose levels are 100 times more concentrated in blood than in saliva, which is why in spite of many efforts to use saliva, diabetics are still pricking themselves to get accurate glucose readings.

But now, harnessing the power of nanotechnology, engineers at Brown University say they've designed a biochip that can measure glucose levels in saliva almost as accurately as current devices can measure levels in blood.

To do this, the engineers etched a complicated array of thousands of plasmonic interferometers (no, this is not an episode of Farscape) onto a fingernail-size biochip. This means they were essentially using … Read more