Imaging tech

Routine mammography's potential harm: Overdiagnosis

Routine mammography screening, widely considered crucial in early breast cancer detection, may in fact be doing its job too well.

It turns out that as many as a quarter of the early cancers detected by mammography would not progress. That suggests early detection results in a great deal of unnecessary treatment and stress, according to a Harvard School of Public Health analysis of a nationwide screening program in Norway.

"Radiologists have been trained to find even the smallest of tumors in a bid to detect as many cancers as possible to be able to cure breast cancer," lead … Read more

MIT study: Light alone can activate specific memories

In a famous surgery in the early 1900s, Canadian neurosurgeon Wilder Penfield, trying to treat epilepsy, found that stimulating specific neurons while patients were under local anesthesia caused them to vividly recall complex events. The mind, then, is based on matter, Penfield concluded.

Now researchers at MIT say they put this observation to the test in a rigorous study showing that the direct reactivation of specific hippocampus neurons can lead to very specific memory recall. And to do this, all they used was light.

"We demonstrate that behavior based on high-level cognition, such as the expression of a specific … Read more

Hi-def fiber tracking helps pinpoint brain damage

When a 32-year-old man crashed his all-terrain vehicle without wearing a helmet, he slipped into a coma for three weeks. Though his initial CT scans revealed bleeding and swelling, and an MRI scan a week into the coma revealed bruising and swelling in the same area, neurosurgeons had no way of knowing precisely how the man would be affected if he did come out of his coma.

Three weeks later, the man awoke without the ability to move his left leg, arm, or hand. Only then were doctors able to begin planning rehabilitation.

Fortunately for the patient, a novel imaging … Read more

Portable device to detect pathogens in 30 minutes

Engineers at Cornell are building a handheld pathogen detector that will help health care workers around the world test for pathogens such as tuberculosis, gonorrhea, and HIV and get results in as little as 30 minutes, instead of waiting days.

Dan Luo, professor of biological and environmental engineering, has been using synthetic DNA to amplify tiny samples of pathogen DNA, RNA, or proteins. Because of $25 million in funding from the Bill & Melinda Gates Foundation's Grand Challenge to 12 teams developing point-of-care diagnostics, Luo will be combining forces with Edwin Kan, a Cornell professor of electrical and computer engineering, who has built a computer chip that can respond quickly to those amplified samples.

The engineers describe their novel device as something akin to a molecular-level Lego builder.… Read more

Use Kinect to teach anatomy? It's a 'Mirracle'!

Kinect hacks have been used for many a grand feat, from a tool that helps the blind navigate more easily to hands-free questing in World of Warcraft and virtual cat brushing.

So why not integrate the powers of Microsoft Kinect with a mirror to teach such subjects as basic anatomy?

For the past year, a team out of the Technical University of Munich in Germany has been working on just that. The researchers use Kinect to estimate the position of a person in front of an augmented-reality mirror in order to create the illusion that the user can see inside … Read more

Lifelens malaria app wins Microsoft 'Imagine Cup' grant

After taking second place in the 2011 Imagine Cup finals, Team Lifelens of the U.S. is one of four teams from around the world to win a $75,000 Imagine Cup grant, Microsoft announced today at the World Economic Forum annual meeting in Davos, Switzerland.

The Lifelens project is run by students at universities across the country who have been working since November 2010 on an app that can image malaria cells for fast diagnosis right there on the phone, sans Internet.

The premise is straightforward. Apply a blood sample to a slide with a dye that only malaria … Read more

DHS' X-ray scanners could be cancer risk to border crossers

Internal Homeland Security documents describing specifications for border-crossing scanners, which emit gamma or X-ray radiation to probe vehicles and their occupants, are raising new health and privacy concerns, CNET has learned.

Even though a public outcry has prompted Homeland Security to move away from adding X-ray machines to airports--it purchased 300 body scanners last year that used alternative technology instead--it appears to be embracing them at U.S.-Mexico land border crossings as an efficient way to detect drugs, currency, and explosives.

A 63-page set of specifications (PDF), heavily redacted, obtained by the Electronic Privacy Information Center through the Freedom … Read more

PET method detects dementia, including Alzheimer's

Ah, we are but mere mortals, and scientific research has a way of reminding us precisely how.

Not only has one recent study found that humans can experience age-related neurological decline as early as 45, but scientists are also reporting in the Journal of Nuclear Medicine that positron emission tomography (PET) can safely and accurately detect dementia early on.

The technique, according to lead author Nicolaas Bohnen in a news release, not only helps diagnose dementia, but also improves physician confidence: "This process can be difficult for physicians, especially when evaluating younger patients or those who have subtle signs … Read more

Photoacoustic device identifies cancer before tumors form

Early detection of skin cancer may soon be possible, thanks to researchers who compare their approach to looking for a black 18-wheeler in an eight-lane highway of white cars.

The new technique for melanoma detection, proposed by researchers at the University of Missouri, uses photoacoustics (laser-induced ultrasound) to find cancer cells before they form into tumors. Testing could cost just a few hundred dollars. The current method of detection, by comparison, requires waiting for tumors to form and can cost thousands of dollars.

"Using a small blood sample, our device and method will provide an earlier diagnosis for aggressive … Read more

About to be taken off life support, man wakes

A young man in a coma was unwittingly poised to give the ultimate this holiday season--his life, and with it, his organs. Instead, his mother became the recipient of the ultimate gift: his sudden recovery.

"Nobody could ever give me a better Christmas present than this--ever, ever, ever," his mother, Susan Regan, told ABC News this week.

Sam Schmid, a junior at the University of Arizona, suffered severe brain damage and broken femurs in a five-car accident in October that killed his friend and roommate.

ABC reports that Schmid was airlifted to the Barrow Neurological Institute in Phoenix, … Read more